Advertisement
Research Article

A Machine Learning Approach for Identifying Novel Cell Type–Specific Transcriptional Regulators of Myogenesis

  • Brian W. Busser equal contributor,

    equal contributor Contributed equally to this work with: Brian W. Busser, Leila Taher

    Affiliation: Laboratory of Developmental Systems Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Leila Taher equal contributor,

    equal contributor Contributed equally to this work with: Brian W. Busser, Leila Taher

    Affiliation: Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Yongsok Kim,

    Affiliation: Laboratory of Developmental Systems Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Terese Tansey,

    Affiliation: Laboratory of Developmental Systems Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Molly J. Bloom,

    Affiliation: Laboratory of Developmental Systems Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Ivan Ovcharenko mail,

    ovcharen@nih.gov (IO); michelsonam@nhlbi.nih.gov (AMM)

    Affiliation: Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Alan M. Michelson mail

    ovcharen@nih.gov (IO); michelsonam@nhlbi.nih.gov (AMM)

    Affiliation: Laboratory of Developmental Systems Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Published: March 08, 2012
  • DOI: 10.1371/journal.pgen.1002531

About the Authors

Brian W. Busser, Yongsok Kim, Terese Tansey, Molly J. Bloom, Alan M. Michelson
Laboratory of Developmental Systems Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Leila Taher, Ivan Ovcharenko
Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BWB LT YK TT IO AMM. Performed the experiments: BWB LT YK TT. Analyzed the data: BWB LT YK TT IO AMM. Contributed reagents/materials/analysis tools: MJB. Wrote the paper: BWB LT IO AMM.