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Research Article

A Quantitative, High-Throughput Reverse Genetic Screen Reveals Novel Connections between Pre–mRNA Splicing and 5′ and 3′ End Transcript Determinants

  • Laura-Oana Albulescu,
  • Nevin Sabet,
  • Mohanram Gudipati,
  • Nicholas Stepankiw,
  • Zane J. Bergman,
  • Tim C. Huffaker,
  • Jeffrey A. Pleiss mail

    jpleiss@cornell.edu

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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  • Published: March 29, 2012
  • DOI: 10.1371/journal.pgen.1002530

About the Authors

Jeffrey A. Pleiss
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

Corresponding Author

Email: jpleiss@cornell.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: L-O Albulescu, JA Pleiss. Performed the experiments: L-O Albulescu, N Sabet, M Gudipati, N Stepankiw, ZJ Bergman, JA Pleiss. Analyzed the data: L-O Albulescu, M Gudipati, N Stepankiw. Contributed reagents/materials/analysis tools: TC Huffaker. Wrote the paper: L-O Albulescu, JA Pleiss.