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Research Article

Discovery of a Modified Tetrapolar Sexual Cycle in Cryptococcus amylolentus and the Evolution of MAT in the Cryptococcus Species Complex

  • Keisha Findley equal contributor,

    equal contributor Contributed equally to this work with: Keisha Findley, Sheng Sun

    Affiliations: Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Sheng Sun equal contributor,

    equal contributor Contributed equally to this work with: Keisha Findley, Sheng Sun

    Affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • James A. Fraser,

    Affiliation: School of Molecular and Microbial Sciences, University of Queensland, Brisbane, Australia

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  • Yen-Ping Hsueh,

    Affiliation: Division of Biology, California Institute of Technology, Pasadena, California, United States of America

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  • Anna Floyd Averette,

    Affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Wenjun Li,

    Affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Fred S. Dietrich,

    Affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Joseph Heitman mail

    heitm001@duke.edu

    Affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Published: February 16, 2012
  • DOI: 10.1371/journal.pgen.1002528

About the Authors

Keisha Findley
Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Keisha Findley, Sheng Sun, Anna Floyd Averette, Wenjun Li, Fred S. Dietrich, Joseph Heitman
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
James A. Fraser
School of Molecular and Microbial Sciences, University of Queensland, Brisbane, Australia
Yen-Ping Hsueh
Division of Biology, California Institute of Technology, Pasadena, California, United States of America

Corresponding Author

Email: heitm001@duke.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KF SS JH. Performed the experiments: KF SS JAF Y-PH AFA WL FSD. Analyzed the data: KF SS JH. Wrote the paper: KF SS JH.