Advertisement
Research Article

Contrasting Properties of Gene-Specific Regulatory, Coding, and Copy Number Mutations in Saccharomyces cerevisiae: Frequency, Effects, and Dominance

  • Jonathan D. Gruber,

    Affiliation: Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Kara Vogel,

    Affiliation: Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Gizem Kalay,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Patricia J. Wittkopp mail

    wittkopp@umich.edu

    Affiliations: Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Published: February 09, 2012
  • DOI: 10.1371/journal.pgen.1002497

About the Authors

Jonathan D. Gruber, Kara Vogel, Patricia J. Wittkopp
Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, United States of America
Gizem Kalay, Patricia J. Wittkopp
Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

Corresponding Author

Email: wittkopp@umich.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PJW JDG GK. Performed the experiments: JDG KV GK. Analyzed the data: JDG PJW KV GK. Contributed reagents/materials/analysis tools: JDG GK. Wrote the paper: PJW JDG.