Advertisement
Research Article

Reduced Lentivirus Susceptibility in Sheep with TMEM154 Mutations

  • Michael P. Heaton mail,

    mike.heaton@ars.usda.gov

    Affiliation: U.S. Meat Animal Research Center, Agriculture Research Service, United States Department of Agriculture, Clay Center, Nebraska, United States of America

    X
  • Michael L. Clawson,

    Affiliation: U.S. Meat Animal Research Center, Agriculture Research Service, United States Department of Agriculture, Clay Center, Nebraska, United States of America

    X
  • Carol G. Chitko-Mckown,

    Affiliation: U.S. Meat Animal Research Center, Agriculture Research Service, United States Department of Agriculture, Clay Center, Nebraska, United States of America

    X
  • Kreg A. Leymaster,

    Affiliation: U.S. Meat Animal Research Center, Agriculture Research Service, United States Department of Agriculture, Clay Center, Nebraska, United States of America

    X
  • Timothy P. L. Smith,

    Affiliation: U.S. Meat Animal Research Center, Agriculture Research Service, United States Department of Agriculture, Clay Center, Nebraska, United States of America

    X
  • Gregory P. Harhay,

    Affiliation: U.S. Meat Animal Research Center, Agriculture Research Service, United States Department of Agriculture, Clay Center, Nebraska, United States of America

    X
  • Stephen N. White,

    Affiliation: Animal Disease Research Unit, Agriculture Research Service, United States Department of Agriculture, Pullman, Washington, United States of America

    X
  • Lynn M. Herrmann-Hoesing,

    Affiliation: Animal Disease Research Unit, Agriculture Research Service, United States Department of Agriculture, Pullman, Washington, United States of America

    X
  • Michelle R. Mousel,

    Affiliation: U.S. Sheep Experiment Station, Agriculture Research Service, United States Department of Agriculture, Dubois, Idaho, United States of America

    X
  • Gregory S. Lewis,

    Affiliation: U.S. Sheep Experiment Station, Agriculture Research Service, United States Department of Agriculture, Dubois, Idaho, United States of America

    X
  • Theodore S. Kalbfleisch,

    Affiliation: Department of Biochemistry and Molecular Biology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America

    X
  • James E. Keen,

    Affiliation: Great Plains Veterinary Educational Center, University of Nebraska, Clay Center, Nebraska, United States of America

    X
  • William W. Laegreid

    Affiliation: Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

    X
  • Published: January 26, 2012
  • DOI: 10.1371/journal.pgen.1002467

About the Authors

Michael P. Heaton, Michael L. Clawson, Carol G. Chitko-Mckown, Kreg A. Leymaster, Timothy P. L. Smith, Gregory P. Harhay
U.S. Meat Animal Research Center, Agriculture Research Service, United States Department of Agriculture, Clay Center, Nebraska, United States of America
Stephen N. White, Lynn M. Herrmann-Hoesing
Animal Disease Research Unit, Agriculture Research Service, United States Department of Agriculture, Pullman, Washington, United States of America
Michelle R. Mousel, Gregory S. Lewis
U.S. Sheep Experiment Station, Agriculture Research Service, United States Department of Agriculture, Dubois, Idaho, United States of America
Theodore S. Kalbfleisch
Department of Biochemistry and Molecular Biology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America
James E. Keen
Great Plains Veterinary Educational Center, University of Nebraska, Clay Center, Nebraska, United States of America
William W. Laegreid
Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

Corresponding Author

Email: mike.heaton@ars.usda.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MPH MLC CGC-M KAL TPLS SNW LMH-H MRM JEK WWL. Performed the experiments: MPH MLC CGC-M KAL TPLS SNW LMH-H MRM JEK WWL. Analyzed the data: MPH MLC CGC-M KAL TPLS SNW LMH-H MRM. Contributed reagents/materials/analysis tools: MPH MLC CGC-M KAL TPLS GPH GSL SNW LMH-H MRM TSK JEK WWL. Wrote the paper: MPH MLC CGC-M KAL TPLS GPH SNW LMH-H MRM GSL TSK JEK WWL.