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Research Article

The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants

  • Sven Vilain,

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Giovanni Esposito,

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Dominik Haddad,

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Onno Schaap,

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Mariya P. Dobreva,

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Melissa Vos,

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Stefanie Van Meensel,

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Vanessa A. Morais,

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Bart De Strooper,

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Patrik Verstreken mail

    patrik.verstreken@cme.vib-kuleuven.be

    Affiliations: VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium, Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

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  • Published: January 05, 2012
  • DOI: 10.1371/journal.pgen.1002456

About the Authors

Sven Vilain, Giovanni Esposito, Dominik Haddad, Onno Schaap, Mariya P. Dobreva, Melissa Vos, Stefanie Van Meensel, Vanessa A. Morais, Bart De Strooper, Patrik Verstreken
VIB Center for Biology of Disease, Katholieke Universiteit Leuven, Leuven, Belgium
Sven Vilain, Giovanni Esposito, Dominik Haddad, Onno Schaap, Mariya P. Dobreva, Melissa Vos, Stefanie Van Meensel, Vanessa A. Morais, Bart De Strooper, Patrik Verstreken
Center for Human Genetics and Leuven Research Institute for Neurodegenerative Diseases (LIND), Katholieke Universiteit Leuven, Leuven, Belgium

Corresponding Author

Email: patrik.verstreken@cme.vib-kuleuven.be

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SV BDS PV. Performed the experiments: SV GE DH OS MPD MV SVM VAM. Analyzed the data: SV GE DH OS MPD MV PV. Contributed reagents/materials/analysis tools: SV VAM. Wrote the paper: SV BDS PV.