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Research Article

Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm

  • Milan Spasic,

    Affiliation: Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany

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  • Caroline C. Friedel,

    Affiliation: Institute for Informatics, Ludwig-Maximilians-Universität (LMU) München, Munich, Germany

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  • Johanna Schott,

    Affiliation: Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany

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  • Jochen Kreth,

    Affiliation: Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany

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  • Kathrin Leppek,

    Affiliation: Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany

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  • Sarah Hofmann,

    Affiliation: Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany

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  • Sevim Ozgur,

    Affiliation: Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany

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  • Georg Stoecklin mail

    g.stoecklin@dkfz.de

    Affiliation: Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany

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  • Published: January 05, 2012
  • DOI: 10.1371/journal.pgen.1002433

About the Authors

Milan Spasic, Johanna Schott, Jochen Kreth, Kathrin Leppek, Sarah Hofmann, Sevim Ozgur, Georg Stoecklin
Helmholtz Junior Research Group Posttranscriptional Control of Gene Expression, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany
Caroline C. Friedel
Institute for Informatics, Ludwig-Maximilians-Universität (LMU) München, Munich, Germany

Corresponding Author

Email: g.stoecklin@dkfz.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MS GS. Performed the experiments: MS JK KL SH SO. Analyzed the data: MS CCF JS GS. Contributed reagents/materials/analysis tools: CCF. Wrote the paper: MS CCF JS GS.