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Research Article

A Complex Genomic Rearrangement Involving the Endothelin 3 Locus Causes Dermal Hyperpigmentation in the Chicken

  • Ben Dorshorst,

    Affiliation: Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

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  • Anna-Maja Molin,

    Affiliation: Science for Life Laboratory, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden

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  • Carl-Johan Rubin,

    Affiliation: Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

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  • Anna M. Johansson,

    Affiliation: Science for Life Laboratory, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden

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  • Lina Strömstedt,

    Affiliation: Science for Life Laboratory, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden

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  • Manh-Hung Pham,

    Affiliation: Department of Animal Science, National Chung-Hsing University, Taichung, Taiwan

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  • Chih-Feng Chen,

    Affiliation: Department of Animal Science, National Chung-Hsing University, Taichung, Taiwan

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  • Finn Hallböök,

    Affiliation: Department of Neuroscience, Uppsala University, Uppsala, Sweden

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  • Chris Ashwell,

    Affiliation: Department of Poultry Science, North Carolina State University, Raleigh, North Carolina, United States of America

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  • Leif Andersson mail

    leif.andersson@imbim.uu.se

    Affiliations: Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden, Science for Life Laboratory, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden

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  • Published: December 22, 2011
  • DOI: 10.1371/journal.pgen.1002412

About the Authors

Ben Dorshorst, Carl-Johan Rubin, Leif Andersson
Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
Anna-Maja Molin, Anna M. Johansson, Lina Strömstedt, Leif Andersson
Science for Life Laboratory, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden
Manh-Hung Pham, Chih-Feng Chen
Department of Animal Science, National Chung-Hsing University, Taichung, Taiwan
Finn Hallböök
Department of Neuroscience, Uppsala University, Uppsala, Sweden
Chris Ashwell
Department of Poultry Science, North Carolina State University, Raleigh, North Carolina, United States of America

Corresponding Author

Email: leif.andersson@imbim.uu.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BD CA LA. Performed the experiments: BD. Analyzed the data: BD A-MM C-JR. Contributed reagents/materials/analysis tools: BD AMJ LS M-HP C-FC CA FH LA. Wrote the paper: BD LA.