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Research Article

PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer

  • Luca Magnani,

    Affiliations: Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America, Institute of Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

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  • Elizabeth B. Ballantyne,

    Affiliations: Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America, Institute of Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

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  • Xiaoyang Zhang,

    Affiliations: Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America, Institute of Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

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  • Mathieu Lupien mail

    Mathieu.Lupien@Dartmouth.edu

    Affiliations: Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America, Institute of Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

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  • Published: November 17, 2011
  • DOI: 10.1371/journal.pgen.1002368

About the Authors

Luca Magnani, Elizabeth B. Ballantyne, Xiaoyang Zhang, Mathieu Lupien
Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America
Luca Magnani, Elizabeth B. Ballantyne, Xiaoyang Zhang, Mathieu Lupien
Institute of Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

Corresponding Author

Email: Mathieu.Lupien@Dartmouth.edu

Competing Interests

Patent pending for the use of PBX1 as a biomarker in breast cancer.

Author Contributions

Conceived and designed the experiments: LM EBB XZ ML. Performed the experiments: LM EBB XZ. Analyzed the data: LM EBB XZ ML. Contributed reagents/materials/analysis tools: LM EBB XZ ML. Wrote the paper: LM ML.