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Research Article

Caenorhabditis elegans Cyclin D/CDK4 and Cyclin E/CDK2 Induce Distinct Cell Cycle Re-Entry Programs in Differentiated Muscle Cells

  • Jerome Korzelius,

    Affiliation: Developmental Biology, Utrecht University, Utrecht, The Netherlands

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  • Inge The,

    Affiliation: Developmental Biology, Utrecht University, Utrecht, The Netherlands

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  • Suzan Ruijtenberg,

    Affiliation: Developmental Biology, Utrecht University, Utrecht, The Netherlands

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  • Martine B. W. Prinsen,

    Affiliation: Developmental Biology, Utrecht University, Utrecht, The Netherlands

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  • Vincent Portegijs,

    Affiliation: Developmental Biology, Utrecht University, Utrecht, The Netherlands

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  • Teije C. Middelkoop,

    Affiliation: Developmental Biology, Utrecht University, Utrecht, The Netherlands

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  • Marian J. Groot Koerkamp,

    Affiliation: Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands

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  • Frank C. P. Holstege,

    Affiliation: Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands

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  • Mike Boxem,

    Affiliation: Developmental Biology, Utrecht University, Utrecht, The Netherlands

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  • Sander van den Heuvel mail

    S.J.L.vandenHeuvel@uu.nl

    Affiliation: Developmental Biology, Utrecht University, Utrecht, The Netherlands

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  • Published: November 10, 2011
  • DOI: 10.1371/journal.pgen.1002362

About the Authors

Jerome Korzelius, Inge The, Suzan Ruijtenberg, Martine B. W. Prinsen, Vincent Portegijs, Teije C. Middelkoop, Mike Boxem, Sander van den Heuvel
Developmental Biology, Utrecht University, Utrecht, The Netherlands
Marian J. Groot Koerkamp, Frank C. P. Holstege
Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands

Corresponding Author

Email: S.J.L.vandenHeuvel@uu.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JK IT SvdH. Performed the experiments: JK IT SR MBWP VP TCM MJGK. Analyzed the data: JK IT SR MJGK MB SvdH. Contributed reagents/materials/analysis tools: MJGK FCPH. Wrote the paper: JK MB SvdH.