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Research Article

Multiple Means to the Same End: The Genetic Basis of Acquired Stress Resistance in Yeast

  • David B. Berry,

    Affiliation: Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Qiaoning Guan,

    Affiliation: Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    Current address: University of California Berkeley, Berkeley, California, United States of America

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  • James Hose,

    Affiliation: Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Suraiya Haroon,

    Affiliation: Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Marinella Gebbia,

    Affiliations: Terrance Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada, Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada

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  • Lawrence E. Heisler,

    Affiliations: Terrance Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada, Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada

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  • Corey Nislow,

    Affiliations: Terrance Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada

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  • Guri Giaever,

    Affiliations: Terrance Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada, Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada

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  • Audrey P. Gasch mail

    agasch@wisc.edu

    Affiliations: Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Genome Center of Wisconsin, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Published: November 10, 2011
  • DOI: 10.1371/journal.pgen.1002353

About the Authors

David B. Berry, Qiaoning Guan, James Hose, Suraiya Haroon, Audrey P. Gasch
Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America
Marinella Gebbia, Lawrence E. Heisler, Corey Nislow, Guri Giaever
Terrance Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada
Marinella Gebbia, Lawrence E. Heisler, Guri Giaever
Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada
Corey Nislow
Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada
Audrey P. Gasch
Genome Center of Wisconsin, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Corresponding Author

Email: agasch@wisc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived experiments: DBB APG. Data analysis, validation, and interpretation: DBB. Designed and conducted selection experiments: DBB QG SH. Designed barcode array hybridizations: CN GG. Performed barcode array hybridizations: MG. Analyzed barcode array hybridizations: LEH. Performed qPCR and assisted in strain validations: JH. Wrote the manuscript: DBB APG.