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Research Article

Transforming Growth Factor β Receptor Type 1 Is Essential for Female Reproductive Tract Integrity and Function

  • Qinglei Li,

    Affiliation: Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

    Current address: Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America

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  • Julio E. Agno,

    Affiliation: Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Mark A. Edson,

    Affiliations: Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Ankur K. Nagaraja,

    Affiliations: Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Takashi Nagashima,

    Affiliation: Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Martin M. Matzuk mail

    mmatzuk@bcm.edu

    Affiliations: Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Department of Pharmacology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Published: October 20, 2011
  • DOI: 10.1371/journal.pgen.1002320

About the Authors

Qinglei Li, Julio E. Agno, Mark A. Edson, Ankur K. Nagaraja, Takashi Nagashima, Martin M. Matzuk
Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America
Mark A. Edson, Martin M. Matzuk
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America
Ankur K. Nagaraja, Martin M. Matzuk
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
Martin M. Matzuk
Department of Pharmacology, Baylor College of Medicine, Houston, Texas, United States of America

Corresponding Author

Email: mmatzuk@bcm.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: QL MMM. Performed the experiments: QL JEA MAE. Analyzed the data: QL MMM. Contributed reagents/materials/analysis tools: AKN TN. Wrote the paper: QL MMM. Revised the manuscript: QL MMM.