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Research Article

Novel Interactions between Actin and the Proteasome Revealed by Complex Haploinsufficiency

  • Brian Haarer,

    Affiliation: Department of Biochemistry and Molecular Biology, Upstate Medical University, State University of New York, Syracuse, New York, United States of America

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  • Dimitra Aggeli,

    Affiliation: Department of Biochemistry and Molecular Biology, Upstate Medical University, State University of New York, Syracuse, New York, United States of America

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  • Susan Viggiano,

    Affiliation: Department of Biochemistry and Molecular Biology, Upstate Medical University, State University of New York, Syracuse, New York, United States of America

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  • Daniel J. Burke,

    Affiliation: Department of Biochemistry and Molecular Genetics, University of Virginia Medical Center, Charlottesville, Virginia, United States of America

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  • David C. Amberg mail

    ambergd@upstate.edu

    Affiliation: Department of Biochemistry and Molecular Biology, Upstate Medical University, State University of New York, Syracuse, New York, United States of America

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  • Published: September 22, 2011
  • DOI: 10.1371/journal.pgen.1002288

About the Authors

Brian Haarer, Dimitra Aggeli, Susan Viggiano, David C. Amberg
Department of Biochemistry and Molecular Biology, Upstate Medical University, State University of New York, Syracuse, New York, United States of America
Daniel J. Burke
Department of Biochemistry and Molecular Genetics, University of Virginia Medical Center, Charlottesville, Virginia, United States of America

Corresponding Author

Email: ambergd@upstate.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BH DJB DCA. Performed the experiments: BH DA SV DCA. Analyzed the data: BH DCA. Contributed reagents/materials/analysis tools: BH DA SV DCA. Wrote the paper: BH DCA.