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Research Article

Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation

  • Jason Gertz equal contributor,

    equal contributor Contributed equally to this work with: Jason Gertz, Katherine E. Varley

    Affiliation: HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America

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  • Katherine E. Varley equal contributor,

    equal contributor Contributed equally to this work with: Jason Gertz, Katherine E. Varley

    Affiliation: HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America

    X
  • Timothy E. Reddy,

    Affiliation: HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America

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  • Kevin M. Bowling,

    Affiliation: HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America

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  • Florencia Pauli,

    Affiliation: HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America

    X
  • Stephanie L. Parker,

    Affiliation: HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America

    X
  • Katerina S. Kucera,

    Affiliation: Duke Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America

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  • Huntington F. Willard,

    Affiliation: Duke Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America

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  • Richard M. Myers mail

    rmyers@hudsonalpha.org

    Affiliation: HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America

    X
  • Published: August 11, 2011
  • DOI: 10.1371/journal.pgen.1002228

About the Authors

Jason Gertz, Katherine E. Varley, Timothy E. Reddy, Kevin M. Bowling, Florencia Pauli, Stephanie L. Parker, Richard M. Myers
HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America
Katerina S. Kucera, Huntington F. Willard
Duke Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America

Corresponding Author

Email: rmyers@hudsonalpha.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JG KEV RMM. Performed the experiments: KEV JG SLP KMB FP. Analyzed the data: JG KEV TER. Contributed reagents/materials/analysis tools: KSK HFW. Wrote the paper: JG.