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Research Article

Ancestral Genes Can Control the Ability of Horizontally Acquired Loci to Confer New Traits

  • H. Deborah Chen,

    Affiliation: Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America

    Current address: Section of Microbial Pathogenesis, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • Mollie W. Jewett,

    Affiliation: Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America

    Current address: Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America

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  • Eduardo A. Groisman mail

    eduardo.groisman@yale.edu

    Affiliations: Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America, Howard Hughes Medical Institute, Washington University School of Medicine, Saint Louis, Missouri, United States of America

    Current address: Section of Microbial Pathogenesis, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • Published: July 21, 2011
  • DOI: 10.1371/journal.pgen.1002184

About the Authors

H. Deborah Chen, Mollie W. Jewett, Eduardo A. Groisman
Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America
Eduardo A. Groisman
Howard Hughes Medical Institute, Washington University School of Medicine, Saint Louis, Missouri, United States of America

Corresponding Author

Email: eduardo.groisman@yale.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HDC MWJ EAG. Performed the experiments: HDC MWJ. Analyzed the data: HDC MWJ EAG. Contributed reagents/materials/analysis tools: HDC MWJ. Wrote the paper: HDC EAG.