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Research Article

NatF Contributes to an Evolutionary Shift in Protein N-Terminal Acetylation and Is Important for Normal Chromosome Segregation

  • Petra Van Damme equal contributor,

    equal contributor Contributed equally to this work with: Petra Van Damme, Kristine Hole, Ana Pimenta-Marques

    Affiliations: Department of Medical Protein Research, Ghent University, Ghent, Belgium, Department of Biochemistry, Ghent University, Ghent, Belgium

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  • Kristine Hole equal contributor,

    equal contributor Contributed equally to this work with: Petra Van Damme, Kristine Hole, Ana Pimenta-Marques

    Affiliations: Department of Molecular Biology, University of Bergen, Bergen, Norway, Department of Surgical Sciences, University of Bergen, Bergen, Norway

    X
  • Ana Pimenta-Marques equal contributor,

    equal contributor Contributed equally to this work with: Petra Van Damme, Kristine Hole, Ana Pimenta-Marques

    Affiliation: Instituto Gulbenkian de Ciência, Oeiras, Portugal

    X
  • Kenny Helsens,

    Affiliations: Department of Medical Protein Research, Ghent University, Ghent, Belgium, Department of Biochemistry, Ghent University, Ghent, Belgium

    X
  • Joël Vandekerckhove,

    Affiliations: Department of Medical Protein Research, Ghent University, Ghent, Belgium, Department of Biochemistry, Ghent University, Ghent, Belgium

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  • Rui G. Martinho,

    Affiliation: Instituto Gulbenkian de Ciência, Oeiras, Portugal

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  • Kris Gevaert,

    Affiliations: Department of Medical Protein Research, Ghent University, Ghent, Belgium, Department of Biochemistry, Ghent University, Ghent, Belgium

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  • Thomas Arnesen mail

    Thomas.Arnesen@mbi.uib.no

    Affiliations: Department of Molecular Biology, University of Bergen, Bergen, Norway, Department of Surgery, Haukeland University Hospital, Bergen, Norway

    X
  • Published: July 07, 2011
  • DOI: 10.1371/journal.pgen.1002169

About the Authors

Petra Van Damme, Kenny Helsens, Joël Vandekerckhove, Kris Gevaert
Department of Medical Protein Research, Ghent University, Ghent, Belgium
Petra Van Damme, Kenny Helsens, Joël Vandekerckhove, Kris Gevaert
Department of Biochemistry, Ghent University, Ghent, Belgium
Kristine Hole, Thomas Arnesen
Department of Molecular Biology, University of Bergen, Bergen, Norway
Kristine Hole
Department of Surgical Sciences, University of Bergen, Bergen, Norway
Ana Pimenta-Marques, Rui G. Martinho
Instituto Gulbenkian de Ciência, Oeiras, Portugal
Thomas Arnesen
Department of Surgery, Haukeland University Hospital, Bergen, Norway

Corresponding Author

Email: Thomas.Arnesen@mbi.uib.no

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: P Van Damme, RG Martinho, K Gevaert, T Arnesen. Performed the experiments: P Van Damme, K Hole, A Pimenta-Marques, K Helsens, T Arnesen. Analyzed the data: P Van Damme, K Hole, A Pimenta-Marques, J Vandekerckhove, RG Martinho, K Gevaert, T Arnesen. Wrote the paper: P Van Damme, K Gevaert, T Arnesen.