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Research Article

The Epistatic Relationship between BRCA2 and the Other RAD51 Mediators in Homologous Recombination

  • Yong Qing equal contributor,

    equal contributor Contributed equally to this work with: Yong Qing, Mitsuyoshi Yamazoe

    Affiliation: Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Mitsuyoshi Yamazoe equal contributor,

    equal contributor Contributed equally to this work with: Yong Qing, Mitsuyoshi Yamazoe

    Affiliation: Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

    X
  • Kouji Hirota,

    Affiliation: Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Donniphat Dejsuphong,

    Affiliation: Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

    X
  • Wataru Sakai,

    Affiliation: Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Kimiyo N. Yamamoto,

    Affiliation: Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Douglas K. Bishop,

    Affiliation: Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America

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  • XiaoHua Wu,

    Affiliation: State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medicinal School, Sichuan University, Chengdu, China

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  • Shunichi Takeda mail

    stakeda@rg.med.kyoto-u.ac.jp

    Affiliation: Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Published: July 14, 2011
  • DOI: 10.1371/journal.pgen.1002148

About the Authors

Yong Qing, Mitsuyoshi Yamazoe, Kouji Hirota, Donniphat Dejsuphong, Wataru Sakai, Kimiyo N. Yamamoto, Shunichi Takeda
Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Douglas K. Bishop
Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
XiaoHua Wu
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medicinal School, Sichuan University, Chengdu, China

Corresponding Author

Email: stakeda@rg.med.kyoto-u.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YQ MY KH ST. Performed the experiments: YQ MY KH DD KNY. Analyzed the data: YQ MY KH DKB XW ST. Contributed reagents/materials/analysis tools: YQ MY KH WS DD KNY XW. Wrote the paper: YQ MY KH ST.