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Research Article

Foxp2 Regulates Gene Networks Implicated in Neurite Outgrowth in the Developing Brain

  • Sonja C. Vernes,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

    Current address: Research Institute of Molecular Pathology, Vienna, Austria

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  • Peter L. Oliver,

    Affiliation: Medical Research Council Functional Genetics Unit, University of Oxford, Oxford, United Kingdom

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  • Elizabeth Spiteri,

    Affiliation: Program in Neurogenetics, Department of Neurology, University of California Los Angeles, Los Angeles, California, United States of America

    Current address: Cedars Sinai Medical Center, Department of Pathology and Laboratory Medicine, Los Angeles, California, United States of America

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  • Helen E. Lockstone,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Rathi Puliyadi,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Jennifer M. Taylor,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Joses Ho,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Cedric Mombereau,

    Affiliation: INSERM Institute du Fer à Moulin, University Pierre and Marie Curie, UMR-S 839, Paris, France

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  • Ariel Brewer,

    Affiliation: INSERM Institute du Fer à Moulin, University Pierre and Marie Curie, UMR-S 839, Paris, France

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  • Ernesto Lowy,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Jérôme Nicod,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Matthias Groszer,

    Affiliations: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, INSERM Institute du Fer à Moulin, University Pierre and Marie Curie, UMR-S 839, Paris, France

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  • Dilair Baban,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Natasha Sahgal,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Jean-Baptiste Cazier,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Jiannis Ragoussis,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Kay E. Davies,

    Affiliation: Medical Research Council Functional Genetics Unit, University of Oxford, Oxford, United Kingdom

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  • Daniel H. Geschwind,

    Affiliations: Program in Neurogenetics, Department of Neurology, University of California Los Angeles, Los Angeles, California, United States of America, Semel Institute and Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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  • Simon E. Fisher mail

    Simon.Fisher@mpi.nl

    Affiliations: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands

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  • Published: July 07, 2011
  • DOI: 10.1371/journal.pgen.1002145

About the Authors

Sonja C. Vernes, Helen E. Lockstone, Rathi Puliyadi, Jennifer M. Taylor, Joses Ho, Ernesto Lowy, Jérôme Nicod, Matthias Groszer, Dilair Baban, Natasha Sahgal, Jean-Baptiste Cazier, Jiannis Ragoussis, Simon E. Fisher
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
Peter L. Oliver, Kay E. Davies
Medical Research Council Functional Genetics Unit, University of Oxford, Oxford, United Kingdom
Elizabeth Spiteri, Daniel H. Geschwind
Program in Neurogenetics, Department of Neurology, University of California Los Angeles, Los Angeles, California, United States of America
Cedric Mombereau, Ariel Brewer, Matthias Groszer
INSERM Institute du Fer à Moulin, University Pierre and Marie Curie, UMR-S 839, Paris, France
Daniel H. Geschwind
Semel Institute and Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America
Simon E. Fisher
Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands

Corresponding Author

Email: Simon.Fisher@mpi.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SCV SEF. Performed the experiments: SCV PLO ES RP JH CM AB JN MG DB. Analyzed the data: SCV HEL JMT EL NS J-BC SEF. Contributed reagents/materials/analysis tools: JR KED DHG SEF. Wrote the paper: SCV SEF.