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Research Article

Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's Disease

  • Chuong B. Do mail,

    cdo@23andme.com (CBD); nick@23andme.com (NE)

    Affiliation: 23andMe, Mountain View, California, United States of America

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  • Joyce Y. Tung,

    Affiliation: 23andMe, Mountain View, California, United States of America

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  • Elizabeth Dorfman,

    Affiliation: 23andMe, Mountain View, California, United States of America

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  • Amy K. Kiefer,

    Affiliation: 23andMe, Mountain View, California, United States of America

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  • Emily M. Drabant,

    Affiliation: 23andMe, Mountain View, California, United States of America

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  • Uta Francke,

    Affiliation: 23andMe, Mountain View, California, United States of America

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  • Joanna L. Mountain,

    Affiliation: 23andMe, Mountain View, California, United States of America

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  • Samuel M. Goldman,

    Affiliation: Parkinson's Institute, Sunnyvale, California, United States of America

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  • Caroline M. Tanner,

    Affiliation: Parkinson's Institute, Sunnyvale, California, United States of America

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  • J. William Langston,

    Affiliation: Parkinson's Institute, Sunnyvale, California, United States of America

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  • Anne Wojcicki,

    Affiliation: 23andMe, Mountain View, California, United States of America

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  • Nicholas Eriksson mail

    cdo@23andme.com (CBD); nick@23andme.com (NE)

    Affiliation: 23andMe, Mountain View, California, United States of America

    X
  • Published: June 23, 2011
  • DOI: 10.1371/journal.pgen.1002141

About the Authors

Chuong B. Do, Joyce Y. Tung, Elizabeth Dorfman, Amy K. Kiefer, Emily M. Drabant, Uta Francke, Joanna L. Mountain, Anne Wojcicki, Nicholas Eriksson
23andMe, Mountain View, California, United States of America
Samuel M. Goldman, Caroline M. Tanner, J. William Langston
Parkinson's Institute, Sunnyvale, California, United States of America

Corresponding Authors

Competing Interests

CBD, JYT, ED, AKK, EMD, UF, JLM, AW, and NE are or have been employed by 23andMe and own stock options in the company. 23andMe CEO AW has provided general guidance, including guidance related to the company's research undertakings and direction. PLoS co-founder Michael B. Eisen is a member of the 23andMe Scientific Advisory Board.

Author Contributions

Conceived and designed the experiments: CBD JYT ED AKK EMD UF JLM SMG CMT JWL AW NE. Performed the experiments: CBD JYT ED AKK EMD UF JLM SMG CMT JWL AW NE. Analyzed the data: CBD NE. Wrote the paper: CBD NE.