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Research Article

Translation Reinitiation Relies on the Interaction between eIF3a/TIF32 and Progressively Folded cis-Acting mRNA Elements Preceding Short uORFs

  • Vanda Munzarová,

    Affiliation: Laboratory of Regulation of Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

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  • Josef Pánek,

    Affiliation: Laboratory of Bioinformatics, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

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  • Stanislava Gunišová,

    Affiliation: Laboratory of Regulation of Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

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  • István Dányi,

    Affiliation: Laboratory of Regulation of Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

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  • Béla Szamecz,

    Affiliation: Laboratory of Regulation of Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

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  • Leoš Shivaya Valášek mail

    valasekl@biomed.cas.cz

    Affiliation: Laboratory of Regulation of Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

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  • Published: July 07, 2011
  • DOI: 10.1371/journal.pgen.1002137

About the Authors

Vanda Munzarová, Stanislava Gunišová, István Dányi, Béla Szamecz, Leoš Shivaya Valášek
Laboratory of Regulation of Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
Josef Pánek
Laboratory of Bioinformatics, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

Corresponding Author

Email: valasekl@biomed.cas.cz

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LSV VM JP. Performed the experiments: VM SG ID. Analyzed the data: LSV VM JP SG. Contributed reagents/materials/analysis tools: BS. Wrote the paper: LSV. Performed the computational analysis: JP. Performed most of the experiments: VM.