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Research Article

Specific SKN-1/Nrf Stress Responses to Perturbations in Translation Elongation and Proteasome Activity

  • Xuan Li,

    Affiliations: Joslin Diabetes Center, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China

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  • Olli Matilainen,

    Affiliation: Research Programs Unit, Molecular Cancer Biology, and Institute of Biomedicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland

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  • Congyu Jin,

    Affiliation: Research Programs Unit, Molecular Cancer Biology, and Institute of Biomedicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland

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  • Kira M. Glover-Cutter,

    Affiliations: Joslin Diabetes Center, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Carina I. Holmberg mail,

    carina.holmberg@helsinki.fi (CIH); keith.blackwell@joslin.harvard.edu (TKB)

    Affiliation: Research Programs Unit, Molecular Cancer Biology, and Institute of Biomedicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland

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  • T. Keith Blackwell mail

    carina.holmberg@helsinki.fi (CIH); keith.blackwell@joslin.harvard.edu (TKB)

    Affiliations: Joslin Diabetes Center, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: June 09, 2011
  • DOI: 10.1371/journal.pgen.1002119

About the Authors

Xuan Li, Kira M. Glover-Cutter, T. Keith Blackwell
Joslin Diabetes Center, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts, United States of America
Xuan Li, Kira M. Glover-Cutter, T. Keith Blackwell
Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
Xuan Li
College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China
Olli Matilainen, Congyu Jin, Carina I. Holmberg
Research Programs Unit, Molecular Cancer Biology, and Institute of Biomedicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TKB CIH XL OM CJ KMG-C. Performed the experiments: XL OM CJ KMG-C. Analyzed the data: XL OM CJ KMG-C. Wrote the paper: XL TKB.