Advertisement
Research Article

Mechanisms for the Evolution of a Derived Function in the Ancestral Glucocorticoid Receptor

  • Sean Michael Carroll,

    Affiliation: Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America

    X
  • Eric A. Ortlund mail,

    joet@uoregon.edu (JWT); eric.ortlund@emory.edu (EO) (Correspondence related to X-ray crystallography)

    Affiliation: Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

    X
  • Joseph W. Thornton mail

    joet@uoregon.edu (JWT); eric.ortlund@emory.edu (EO) (Correspondence related to X-ray crystallography)

    Affiliation: Howard Hughes Medical Institute, Center for Ecology and Evolutionary Biology, University of Oregon, Eugene, Oregon, United States of America

    X
  • Published: June 16, 2011
  • DOI: 10.1371/journal.pgen.1002117

About the Authors

Sean Michael Carroll
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America
Eric A. Ortlund
Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America
Joseph W. Thornton
Howard Hughes Medical Institute, Center for Ecology and Evolutionary Biology, University of Oregon, Eugene, Oregon, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SMC EAO JWT. Performed the experiments: SMC EAO JWT. Analyzed the data: SMC EAO JWT. Wrote the paper: SMC EAO JWT.