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Research Article

A Large-Scale Complex Haploinsufficiency-Based Genetic Interaction Screen in Candida albicans: Analysis of the RAM Network during Morphogenesis

  • Nike Bharucha equal contributor,

    equal contributor Contributed equally to this work with: Nike Bharucha, Yeissa Chabrier-Roselló

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Yeissa Chabrier-Roselló equal contributor,

    equal contributor Contributed equally to this work with: Nike Bharucha, Yeissa Chabrier-Roselló

    Affiliation: Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America

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  • Tao Xu,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Cole Johnson,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Sarah Sobczynski,

    Affiliation: Department of Microbiology/Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America

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  • Qingxuan Song,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Craig J. Dobry,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Matthew J. Eckwahl,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Christopher P. Anderson,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Andrew J. Benjamin,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Anuj Kumar mail,

    damian_krysan@urmc.rochester.edu (DJK); anujk@umich.edu (AK)

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Damian J. Krysan mail

    damian_krysan@urmc.rochester.edu (DJK); anujk@umich.edu (AK)

    Affiliations: Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America, Department of Microbiology/Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America

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  • Published: April 28, 2011
  • DOI: 10.1371/journal.pgen.1002058

About the Authors

Nike Bharucha, Tao Xu, Cole Johnson, Qingxuan Song, Craig J. Dobry, Matthew J. Eckwahl, Christopher P. Anderson, Andrew J. Benjamin, Anuj Kumar
Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America
Yeissa Chabrier-Roselló, Damian J. Krysan
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
Sarah Sobczynski, Damian J. Krysan
Department of Microbiology/Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NB YC-R AK DJK. Performed the experiments: NB YC-R TX CJ SS QS CJD MJE CPA AJB DJK. Analyzed the data: NB YC-R TX CJ SS AK DJK. Contributed reagents/materials/analysis tools: NB YC-R TX CJ SS QS CJD MJE CPA AJB DJK. Wrote the paper: YC-R AK DJK.