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Research Article

Evolution of Vertebrate Transient Receptor Potential Vanilloid 3 Channels: Opposite Temperature Sensitivity between Mammals and Western Clawed Frogs

  • Shigeru Saito mail,

    sshigeru@nips.ac.jp (SS); tominaga@nips.ac.jp (MT)

    Affiliation: Division of Cell Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi, Japan

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  • Naomi Fukuta,

    Affiliation: Division of Cell Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi, Japan

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  • Ryuzo Shingai,

    Affiliation: Laboratory of Bioscience, Faculty of Engineering, Iwate University, Morioka, Iwate, Japan

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  • Makoto Tominaga mail

    sshigeru@nips.ac.jp (SS); tominaga@nips.ac.jp (MT)

    Affiliations: Division of Cell Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi, Japan, Department of Physiological Sciences, The Graduate University for Advanced Studies, Okazaki, Aichi, Japan

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  • Published: April 07, 2011
  • DOI: 10.1371/journal.pgen.1002041

About the Authors

Shigeru Saito, Naomi Fukuta, Makoto Tominaga
Division of Cell Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi, Japan
Ryuzo Shingai
Laboratory of Bioscience, Faculty of Engineering, Iwate University, Morioka, Iwate, Japan
Makoto Tominaga
Department of Physiological Sciences, The Graduate University for Advanced Studies, Okazaki, Aichi, Japan

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SS MT. Performed the experiments: SS NF. Analyzed the data: SS. Contributed reagents/materials/analysis tools: RS MT. Wrote the paper: SS MT.