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Research Article

A Sustained Dietary Change Increases Epigenetic Variation in Isogenic Mice

  • Cheryl C. Y. Li equal contributor,

    equal contributor Contributed equally to this work with: Cheryl C. Y. Li, Jennifer E. Cropley

    Affiliations: Victor Chang Cardiac Research Institute, University of New South Wales, Sydney, Australia, Faculty of Medicine, University of New South Wales, Sydney, Australia

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  • Jennifer E. Cropley equal contributor,

    equal contributor Contributed equally to this work with: Cheryl C. Y. Li, Jennifer E. Cropley

    Affiliations: Victor Chang Cardiac Research Institute, University of New South Wales, Sydney, Australia, Faculty of Medicine, University of New South Wales, Sydney, Australia

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  • Mark J. Cowley,

    Affiliations: Peter Wills Bioinformatics Centre, Garvan Institute of Medical Research, Sydney, Australia, Cancer Research Program, Garvan Institute of Medical Research, Sydney, Australia

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  • Thomas Preiss,

    Affiliations: Victor Chang Cardiac Research Institute, University of New South Wales, Sydney, Australia, Faculty of Medicine, University of New South Wales, Sydney, Australia, Faculty of Science, University of New South Wales, Sydney, Australia

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  • David I. K. Martin,

    Affiliation: Children's Hospital Oakland Research Institute, Oakland, California, United States of America

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  • Catherine M. Suter mail

    c.suter@victorchang.edu.au

    Affiliations: Victor Chang Cardiac Research Institute, University of New South Wales, Sydney, Australia, Faculty of Medicine, University of New South Wales, Sydney, Australia

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  • Published: April 21, 2011
  • DOI: 10.1371/journal.pgen.1001380

About the Authors

Cheryl C. Y. Li, Jennifer E. Cropley, Thomas Preiss, Catherine M. Suter
Victor Chang Cardiac Research Institute, University of New South Wales, Sydney, Australia
Cheryl C. Y. Li, Jennifer E. Cropley, Thomas Preiss, Catherine M. Suter
Faculty of Medicine, University of New South Wales, Sydney, Australia
Mark J. Cowley
Peter Wills Bioinformatics Centre, Garvan Institute of Medical Research, Sydney, Australia
Mark J. Cowley
Cancer Research Program, Garvan Institute of Medical Research, Sydney, Australia
Thomas Preiss
Faculty of Science, University of New South Wales, Sydney, Australia
David I. K. Martin
Children's Hospital Oakland Research Institute, Oakland, California, United States of America

Corresponding Author

Email: c.suter@victorchang.edu.au

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CCYL JEC CMS. Performed the experiments: CCYL. Analyzed the data: CCYL JEC MJC TP DIKM CMS. Wrote the paper: CCYL JEC MJC TP DIKM CMS.