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Research Article

The Toll-Like Receptor Gene Family Is Integrated into Human DNA Damage and p53 Networks

  • Daniel Menendez equal contributor,

    equal contributor Contributed equally to this work with: Daniel Menendez, Maria Shatz

    Affiliation: Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

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  • Maria Shatz equal contributor,

    equal contributor Contributed equally to this work with: Daniel Menendez, Maria Shatz

    Affiliation: Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

    X
  • Kathleen Azzam,

    Affiliation: Host Defense Group, Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

    X
  • Stavros Garantziotis,

    Affiliation: Clinical Research Unit, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

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  • Michael B. Fessler,

    Affiliation: Host Defense Group, Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

    X
  • Michael A. Resnick mail

    resnick@niehs.nih.gov

    Affiliation: Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

    X
  • Published: March 31, 2011
  • DOI: 10.1371/journal.pgen.1001360

About the Authors

Daniel Menendez, Maria Shatz, Michael A. Resnick
Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
Kathleen Azzam, Michael B. Fessler
Host Defense Group, Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
Stavros Garantziotis
Clinical Research Unit, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

Corresponding Author

Email: resnick@niehs.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DM MS SG MBF MAR. Performed the experiments: DM MS KA. Analyzed the data: DM MS SG MBF MAR. Contributed reagents/materials/analysis tools: DM SG MBF MAR. Wrote the paper: DM MS SG MBF MAR.