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Research Article

Incorporating Biological Pathways via a Markov Random Field Model in Genome-Wide Association Studies

  • Min Chen,

    Affiliation: Division of Biostatistics, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Judy Cho,

    Affiliation: Internal Medicine, Yale University, New Haven, Connecticut, United States of America

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  • Hongyu Zhao mail

    hongyu.zhao@yale.edu

    Affiliation: Center for Statistical Genomics and Proteomics, Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut, United States of America

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  • Published: April 07, 2011
  • DOI: 10.1371/journal.pgen.1001353

About the Authors

Min Chen
Division of Biostatistics, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
Judy Cho
Internal Medicine, Yale University, New Haven, Connecticut, United States of America
Hongyu Zhao
Center for Statistical Genomics and Proteomics, Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut, United States of America

Corresponding Author

Email: hongyu.zhao@yale.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JC HZ. Performed the experiments: JC. Analyzed the data: MC. Wrote the paper: MC HZ.