Advertisement
Research Article

Viral Genome Segmentation Can Result from a Trade-Off between Genetic Content and Particle Stability

  • Samuel Ojosnegros,

    Affiliation: Centro de Biología Molecular “Severo Ochoa,” CSIC-UAM, Madrid, Spain

    Current address: California Institute of Technology, Division of Biology, Pasadena, California, United States of America

    X
  • Juan García-Arriaza,

    Affiliations: Centro de Biología Molecular “Severo Ochoa,” CSIC-UAM, Madrid, Spain, Centro Nacional de Biotecnología, CSIC, Madrid, Spain

    X
  • Cristina Escarmís,

    Affiliation: Centro de Biología Molecular “Severo Ochoa,” CSIC-UAM, Madrid, Spain

    X
  • Susanna C. Manrubia,

    Affiliation: Laboratorio de Evolución Molecular, Centro de Astrobiología (CSIC/INTA), Instituto Nacional de Técnica Aeroespacial, Madrid, Spain

    X
  • Celia Perales,

    Affiliation: Centro de Biología Molecular “Severo Ochoa,” CSIC-UAM, Madrid, Spain

    X
  • Armando Arias,

    Affiliation: Centro de Biología Molecular “Severo Ochoa,” CSIC-UAM, Madrid, Spain

    Current address: Department of Virology, Imperial College London, London, United Kingdom

    X
  • Mauricio García Mateu,

    Affiliation: Centro de Biología Molecular “Severo Ochoa,” CSIC-UAM, Madrid, Spain

    X
  • Esteban Domingo mail

    edomingo@cbm.uam.es

    Affiliations: Centro de Biología Molecular “Severo Ochoa,” CSIC-UAM, Madrid, Spain, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain

    X
  • Published: March 17, 2011
  • DOI: 10.1371/journal.pgen.1001344

About the Authors

Samuel Ojosnegros, Juan García-Arriaza, Cristina Escarmís, Celia Perales, Armando Arias, Mauricio García Mateu, Esteban Domingo
Centro de Biología Molecular “Severo Ochoa,” CSIC-UAM, Madrid, Spain
Juan García-Arriaza
Centro Nacional de Biotecnología, CSIC, Madrid, Spain
Susanna C. Manrubia
Laboratorio de Evolución Molecular, Centro de Astrobiología (CSIC/INTA), Instituto Nacional de Técnica Aeroespacial, Madrid, Spain
Esteban Domingo
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain

Corresponding Author

Email: edomingo@cbm.uam.es

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SO CE SCM ED. Performed the experiments: SO CP MGM. Analyzed the data: SO JGA CE SCM CP MGM ED. Contributed reagents/materials/analysis tools: JGA AA. Wrote the paper: SO SCM MGM ED.