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Research Article

Correlated Evolution of Nearby Residues in Drosophilid Proteins

  • Benjamin Callahan mail,

    benjc@stanford.edu

    Affiliation: Department of Applied Physics, Stanford University, Stanford, California, United States of America

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  • Richard A. Neher,

    Affiliation: Kavli Institute for Theoretical Physics, University of California Santa Barbara, Santa Barbara, California, United States of America

    Current address: Max-Planck-Institute for Developmental Biology, Tübingen, Germany

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  • Doris Bachtrog,

    Affiliation: Department of Integrative Biology and Center for Theoretical Evolutionary Genomics, University of California Berkeley, Berkeley, California, United States of America

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  • Peter Andolfatto,

    Affiliation: Department of Ecology and Evolutionary Biology and the Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

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  • Boris I. Shraiman

    Affiliations: Kavli Institute for Theoretical Physics, University of California Santa Barbara, Santa Barbara, California, United States of America, Department of Physics, University of California Santa Barbara, Santa Barbara, California, United States of America

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  • Published: February 24, 2011
  • DOI: 10.1371/journal.pgen.1001315

About the Authors

Benjamin Callahan
Department of Applied Physics, Stanford University, Stanford, California, United States of America
Richard A. Neher, Boris I. Shraiman
Kavli Institute for Theoretical Physics, University of California Santa Barbara, Santa Barbara, California, United States of America
Doris Bachtrog
Department of Integrative Biology and Center for Theoretical Evolutionary Genomics, University of California Berkeley, Berkeley, California, United States of America
Peter Andolfatto
Department of Ecology and Evolutionary Biology and the Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
Boris I. Shraiman
Department of Physics, University of California Santa Barbara, Santa Barbara, California, United States of America

Corresponding Author

Email: benjc@stanford.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BC BIS. Performed the experiments: DB PA. Analyzed the data: BC RAN. Contributed reagents/materials/analysis tools: BC DB PA. Wrote the paper: BC RAN PA BIS.