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Research Article

[SWI+], the Prion Formed by the Chromatin Remodeling Factor Swi1, Is Highly Sensitive to Alterations in Hsp70 Chaperone System Activity

  • Justin K. Hines equal contributor,

    equal contributor Contributed equally to this work with: Justin K. Hines, Xiaomo Li

    Affiliation: Department of Biochemistry, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Xiaomo Li equal contributor,

    equal contributor Contributed equally to this work with: Justin K. Hines, Xiaomo Li

    Affiliation: Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Zhiqiang Du,

    Affiliation: Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

    X
  • Takashi Higurashi,

    Affiliation: Department of Biochemistry, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    Current address: EVEC, Sapporo, Japan

    X
  • Liming Li mail,

    ecraig@wisc.edu (EAC); limingli@northwestern.edu (LL)

    Affiliation: Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

    X
  • Elizabeth A. Craig mail

    ecraig@wisc.edu (EAC); limingli@northwestern.edu (LL)

    Affiliation: Department of Biochemistry, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    X
  • Published: February 17, 2011
  • DOI: 10.1371/journal.pgen.1001309

About the Authors

Justin K. Hines, Takashi Higurashi, Elizabeth A. Craig
Department of Biochemistry, University of Wisconsin–Madison, Madison, Wisconsin, United States of America
Xiaomo Li, Zhiqiang Du, Liming Li
Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JKH XL ZD TH LL EAC. Performed the experiments: JKH XL ZD TH. Analyzed the data: JKH XL ZD TH LL EAC. Wrote the paper: JKH XL LL EAC.