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Research Article

Self-Mating in the Definitive Host Potentiates Clonal Outbreaks of the Apicomplexan Parasites Sarcocystis neurona and Toxoplasma gondii

  • Jered M. Wendte,

    Affiliations: Molecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Veterinary Pathobiology, Oklahoma State University Center for Veterinary Health Sciences, Stillwater, Oklahoma, United States of America, Howard Hughes Medical Institute–National Institutes of Health Research Scholars Program, Bethesda, Maryland, United States of America

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  • Melissa A. Miller,

    Affiliation: Marine Wildlife Veterinary Care and Research Center (CDFG-OSPR), Santa Cruz, California, United States of America

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  • Dyanna M. Lambourn,

    Affiliation: Washington Department of Fish and Wildlife, Lakewood, Washington, United States of America

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  • Spencer L. Magargal,

    Affiliation: Molecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • David A. Jessup,

    Affiliation: Marine Wildlife Veterinary Care and Research Center (CDFG-OSPR), Santa Cruz, California, United States of America

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  • Michael E. Grigg mail

    griggm@niaid.nih.gov

    Affiliations: Molecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Veterinary Pathobiology, Oklahoma State University Center for Veterinary Health Sciences, Stillwater, Oklahoma, United States of America

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  • Published: December 23, 2010
  • DOI: 10.1371/journal.pgen.1001261

About the Authors

Jered M. Wendte, Spencer L. Magargal, Michael E. Grigg
Molecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
Jered M. Wendte, Michael E. Grigg
Department of Veterinary Pathobiology, Oklahoma State University Center for Veterinary Health Sciences, Stillwater, Oklahoma, United States of America
Jered M. Wendte
Howard Hughes Medical Institute–National Institutes of Health Research Scholars Program, Bethesda, Maryland, United States of America
Melissa A. Miller, David A. Jessup
Marine Wildlife Veterinary Care and Research Center (CDFG-OSPR), Santa Cruz, California, United States of America
Dyanna M. Lambourn
Washington Department of Fish and Wildlife, Lakewood, Washington, United States of America

Corresponding Author

Email: griggm@niaid.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JMW MEG. Performed the experiments: JMW SLM. Analyzed the data: JMW MAM MEG. Contributed reagents/materials/analysis tools: MAM DML DAJ. Wrote the paper: JMW MEG.