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Research Article

Commercially Available Outbred Mice for Genome-Wide Association Studies

  • Binnaz Yalcin,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Jérôme Nicod,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Amarjit Bhomra,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Stuart Davidson,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • James Cleak,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Laurent Farinelli,

    Affiliation: Fasteris, Plan-les-Ouates, Switzerland

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  • Magne Østerås,

    Affiliation: Fasteris, Plan-les-Ouates, Switzerland

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  • Adam Whitley,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Wei Yuan,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Xiangchao Gan,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Martin Goodson,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Paul Klenerman,

    Affiliation: Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

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  • Ansu Satpathy,

    Affiliation: Section on Immunology and Immunogenetics, Joslin Diabetes Center and Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Diane Mathis,

    Affiliation: Section on Immunology and Immunogenetics, Joslin Diabetes Center and Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Christophe Benoist,

    Affiliation: Section on Immunology and Immunogenetics, Joslin Diabetes Center and Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • David J. Adams,

    Affiliation: Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom

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  • Richard Mott,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Jonathan Flint mail

    jf@well.ox.ac.uk

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Published: September 02, 2010
  • DOI: 10.1371/journal.pgen.1001085

About the Authors

Binnaz Yalcin, Jérôme Nicod, Amarjit Bhomra, Stuart Davidson, James Cleak, Adam Whitley, Wei Yuan, Xiangchao Gan, Martin Goodson, Richard Mott, Jonathan Flint
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
Laurent Farinelli, Magne Østerås
Fasteris, Plan-les-Ouates, Switzerland
Paul Klenerman
Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
Ansu Satpathy, Diane Mathis, Christophe Benoist
Section on Immunology and Immunogenetics, Joslin Diabetes Center and Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America
David J. Adams
Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom

Corresponding Author

Email: jf@well.ox.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BY JN CB RM JF. Performed the experiments: BY JN AB SD JC LF ØM AW PK AS DM DJA. Analyzed the data: BY WY XCG MG PK CB DJA RM JF. Contributed reagents/materials/analysis tools: BY JN AB SD JC AW. Wrote the paper: BY CB RM JF.