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Research Article

Tuberous Sclerosis Complex 1 Regulates dE2F1 Expression during Development and Cooperates with RBF1 to Control Proliferation and Survival

  • Ting-Chiu Hsieh,

    Affiliation: Department of Biology, Developmental Biology Research Initiative, McGill University, Montreal, Canada

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  • Brandon N. Nicolay,

    Affiliation: Department of Biochemistry and Molecular Genetics, University of Illinois Chicago, Chicago, Illinois, United States of America

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  • Maxim V. Frolov,

    Affiliation: Department of Biochemistry and Molecular Genetics, University of Illinois Chicago, Chicago, Illinois, United States of America

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  • Nam-Sung Moon mail

    nam.moon@mcgill.ca

    Affiliation: Department of Biology, Developmental Biology Research Initiative, McGill University, Montreal, Canada

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  • Published: August 19, 2010
  • DOI: 10.1371/journal.pgen.1001071

About the Authors

Ting-Chiu Hsieh, Nam-Sung Moon
Department of Biology, Developmental Biology Research Initiative, McGill University, Montreal, Canada
Brandon N. Nicolay, Maxim V. Frolov
Department of Biochemistry and Molecular Genetics, University of Illinois Chicago, Chicago, Illinois, United States of America

Corresponding Author

Email: nam.moon@mcgill.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TCH NSM. Performed the experiments: TCH NSM. Analyzed the data: TCH NSM. Contributed reagents/materials/analysis tools: TCH BNN MVF. Wrote the paper: TCH BNN MVF NSM.