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Research Article

The Transcriptomes of Two Heritable Cell Types Illuminate the Circuit Governing Their Differentiation

  • Brian B. Tuch equal contributor,

    equal contributor Contributed equally to this work with: Brian B. Tuch, Quinn M. Mitrovich

    Affiliations: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America, Genetic Systems Division, Research and Development, Life Technologies, Foster City, California, United States of America

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  • Quinn M. Mitrovich equal contributor,

    equal contributor Contributed equally to this work with: Brian B. Tuch, Quinn M. Mitrovich

    Affiliation: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America

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  • Oliver R. Homann,

    Affiliation: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America

    X
  • Aaron D. Hernday,

    Affiliation: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America

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  • Cinna K. Monighetti,

    Affiliation: Genetic Systems Division, Research and Development, Life Technologies, Foster City, California, United States of America

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  • Francisco M. De La Vega,

    Affiliation: Genetic Systems Division, Research and Development, Life Technologies, Foster City, California, United States of America

    X
  • Alexander D. Johnson mail

    ajohnson@cgl.ucsf.edu

    Affiliations: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America, Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

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  • Published: August 19, 2010
  • DOI: 10.1371/journal.pgen.1001070

About the Authors

Brian B. Tuch, Quinn M. Mitrovich, Oliver R. Homann, Aaron D. Hernday, Alexander D. Johnson
Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America
Brian B. Tuch, Cinna K. Monighetti, Francisco M. De La Vega
Genetic Systems Division, Research and Development, Life Technologies, Foster City, California, United States of America
Alexander D. Johnson
Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

Corresponding Author

Email: ajohnson@cgl.ucsf.edu

Competing Interests

Some of the authors (BBT, CKM, FMD) of this manuscript are or were employees of Life Technologies, which manufactures the sequencing instrument and some materials used in this study.

Author Contributions

Conceived and designed the experiments: BBT QMM FMDLV ADJ. Performed the experiments: QMM ADH CKM. Analyzed the data: BBT QMM. Contributed reagents/materials/analysis tools: BBT QMM ORH FMDLV. Wrote the paper: BBT QMM ADJ.