# wombat urls ß PLOS Genetics: The Fitness Landscapes of cis-Acting Binding Sites in Different Promoter and Environmental Contexts
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Research Article

The Fitness Landscapes of cis-Acting Binding Sites in Different Promoter and Environmental Contexts

  • Ryan K. Shultzaberger,

    Affiliation: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America

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  • Daniel S. Malashock,

    Affiliation: Graduate Group in Comparative Biochemistry, University of California Berkeley, Berkeley, California, United States of America

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  • Jack F. Kirsch,

    Affiliations: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America, Department of Chemistry, University of California Berkeley, Berkeley, California, United States of America

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  • Michael B. Eisen mail

    mbeisen@berkeley.edu

    Affiliations: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America, Howard Hughes Medical Institute, University of California Berkeley, Berkeley, California, United States of America, California Institute of Quantitative Biosciences, University of California Berkeley, Berkeley, California, United States of America, Genomics Division, Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

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  • Published: July 29, 2010
  • DOI: 10.1371/journal.pgen.1001042

About the Authors

Ryan K. Shultzaberger, Jack F. Kirsch, Michael B. Eisen
Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America
Daniel S. Malashock
Graduate Group in Comparative Biochemistry, University of California Berkeley, Berkeley, California, United States of America
Jack F. Kirsch
Department of Chemistry, University of California Berkeley, Berkeley, California, United States of America
Michael B. Eisen
Howard Hughes Medical Institute, University of California Berkeley, Berkeley, California, United States of America
Michael B. Eisen
California Institute of Quantitative Biosciences, University of California Berkeley, Berkeley, California, United States of America
Michael B. Eisen
Genomics Division, Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

Corresponding Author

Email: mbeisen@berkeley.edu

Competing Interests

MBE is a co-founder and member of the board of directors of PLoS.

Author Contributions

Conceived and designed the experiments: RKS DSM JFK MBE. Performed the experiments: RKS. Analyzed the data: RKS. Contributed reagents/materials/analysis tools: RKS. Wrote the paper: RKS JFK MBE.