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Research Article

The Caenorhabditis elegans Homolog of Gen1/Yen1 Resolvases Links DNA Damage Signaling to DNA Double-Strand Break Repair

  • Aymeric P. Bailly,

    Affiliation: Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee, Dundee, United Kingdom

    X
  • Alasdair Freeman equal contributor,

    equal contributor Contributed equally to this work with: Alasdair Freeman, Julie Hall, Anne-Cécile Déclais

    Affiliation: Cancer Research United Kingdom Nucleic Acid Structure Research Group, University of Dundee, Dundee, United Kingdom

    X
  • Julie Hall equal contributor,

    equal contributor Contributed equally to this work with: Alasdair Freeman, Julie Hall, Anne-Cécile Déclais

    Affiliation: Department of Genetics and Department of Biology, University of North Carolina, Chapel Hill, North Carolina, United States of America

    Current address: Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, North Carolina, United States of America

    X
  • Anne-Cécile Déclais equal contributor,

    equal contributor Contributed equally to this work with: Alasdair Freeman, Julie Hall, Anne-Cécile Déclais

    Affiliation: Cancer Research United Kingdom Nucleic Acid Structure Research Group, University of Dundee, Dundee, United Kingdom

    X
  • Arno Alpi,

    Affiliation: Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee, Dundee, United Kingdom

    Current address: The Scottish Institute for Cell Signalling, University of Dundee, Dundee, United Kingdom

    X
  • David M. J. Lilley,

    Affiliation: Cancer Research United Kingdom Nucleic Acid Structure Research Group, University of Dundee, Dundee, United Kingdom

    X
  • Shawn Ahmed,

    Affiliation: Department of Genetics and Department of Biology, University of North Carolina, Chapel Hill, North Carolina, United States of America

    X
  • Anton Gartner mail

    a.gartner@dundee.ac.uk

    Affiliation: Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee, Dundee, United Kingdom

    X
  • Published: July 15, 2010
  • DOI: 10.1371/journal.pgen.1001025

About the Authors

Aymeric P. Bailly, Arno Alpi, Anton Gartner
Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee, Dundee, United Kingdom
Alasdair Freeman, Anne-Cécile Déclais, David M. J. Lilley
Cancer Research United Kingdom Nucleic Acid Structure Research Group, University of Dundee, Dundee, United Kingdom
Julie Hall, Shawn Ahmed
Department of Genetics and Department of Biology, University of North Carolina, Chapel Hill, North Carolina, United States of America

Corresponding Author

Email: a.gartner@dundee.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: APB DMJL SA AG. Performed the experiments: APB AF JH ACD AA. Analyzed the data: APB AF JH ACD AA DMJL SA AG. Contributed reagents/materials/analysis tools: APB AF JH ACD AA DMJL SA. Wrote the paper: APB DMJL SA AG.