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Research Article

FACT Prevents the Accumulation of Free Histones Evicted from Transcribed Chromatin and a Subsequent Cell Cycle Delay in G1

  • Macarena Morillo-Huesca equal contributor,

    equal contributor Contributed equally to this work with: Macarena Morillo-Huesca, Douglas Maya

    Affiliation: Departamento de Genética, Universidad de Sevilla, Seville, Spain

    X
  • Douglas Maya equal contributor,

    equal contributor Contributed equally to this work with: Macarena Morillo-Huesca, Douglas Maya

    Affiliation: Departamento de Genética, Universidad de Sevilla, Seville, Spain

    X
  • Mari Cruz Muñoz-Centeno mail,

    schavez@us.es (SC); mcmunoz@us.es (MCM-C)

    Affiliation: Departamento de Genética, Universidad de Sevilla, Seville, Spain

    These authors were joint senior authors of this work.

    X
  • Rakesh Kumar Singh,

    Affiliation: Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida, United States of America

    X
  • Vincent Oreal,

    Affiliation: Laboratoire d'Instabilité Génétique et Cancérogenèse, Institut de Biologie Struturale et Microbiologie, Centre National de la Recherche Scientifique, Marseille, France

    X
  • Gajjalaiahvari Ugander Reddy,

    Affiliation: Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida, United States of America

    X
  • Dun Liang,

    Affiliation: Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida, United States of America

    X
  • Vincent Géli,

    Affiliation: Laboratoire d'Instabilité Génétique et Cancérogenèse, Institut de Biologie Struturale et Microbiologie, Centre National de la Recherche Scientifique, Marseille, France

    X
  • Akash Gunjan,

    Affiliation: Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida, United States of America

    X
  • Sebastián Chávez mail

    schavez@us.es (SC); mcmunoz@us.es (MCM-C)

    Affiliation: Departamento de Genética, Universidad de Sevilla, Seville, Spain

    These authors were joint senior authors of this work.

    X
  • Published: May 20, 2010
  • DOI: 10.1371/journal.pgen.1000964

About the Authors

Macarena Morillo-Huesca, Douglas Maya, Mari Cruz Muñoz-Centeno, Sebastián Chávez
Departamento de Genética, Universidad de Sevilla, Seville, Spain
Rakesh Kumar Singh, Gajjalaiahvari Ugander Reddy, Dun Liang, Akash Gunjan
Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida, United States of America
Vincent Oreal, Vincent Géli
Laboratoire d'Instabilité Génétique et Cancérogenèse, Institut de Biologie Struturale et Microbiologie, Centre National de la Recherche Scientifique, Marseille, France

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MMH DM MCMC RKS VG AG SC. Performed the experiments: MMH DM MCMC VO GUR DL. Analyzed the data: MMH DM MCMC RKS VO GUR DL VG AG SC. Wrote the paper: MCMC RKS VG AG SC.