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Research Article

Cdh11 Acts as a Tumor Suppressor in a Murine Retinoblastoma Model by Facilitating Tumor Cell Death

  • Mellone N. Marchong,

    Affiliations: Campbell Family Institute for Cancer Research, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

    Current address: Medical Research Council Cancer Cell Unit, Hutchison/Medical Research Council Research Centre, Cambridge, United Kingdom

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  • Christine Yurkowski,

    Affiliations: Campbell Family Institute for Cancer Research, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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  • Clement Ma,

    Affiliation: Department of Biostatistics, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada

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  • Clarellen Spencer,

    Affiliation: Campbell Family Institute for Cancer Research, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada

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  • Sanja Pajovic,

    Affiliation: Campbell Family Institute for Cancer Research, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada

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  • Brenda L. Gallie mail

    gallie@attglobal.net

    Affiliations: Campbell Family Institute for Cancer Research, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Department of Biostatistics, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada, Department of Ophthalmology, University of Toronto, Toronto, Ontario, Canada

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  • Published: April 22, 2010
  • DOI: 10.1371/journal.pgen.1000923

About the Authors

Mellone N. Marchong, Christine Yurkowski, Clarellen Spencer, Sanja Pajovic, Brenda L. Gallie
Campbell Family Institute for Cancer Research, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
Mellone N. Marchong, Brenda L. Gallie
Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
Christine Yurkowski, Brenda L. Gallie
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
Clement Ma, Brenda L. Gallie
Department of Biostatistics, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
Brenda L. Gallie
Department of Ophthalmology, University of Toronto, Toronto, Ontario, Canada

Corresponding Author

Email: gallie@attglobal.net

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MNM CY SP BLG. Performed the experiments: MNM CY CS SP. Analyzed the data: MNM CY CM SP. Contributed reagents/materials/analysis tools: MNM CY. Wrote the paper: MNM CY BLG.