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Research Article

Maize Inbreds Exhibit High Levels of Copy Number Variation (CNV) and Presence/Absence Variation (PAV) in Genome Content

  • Nathan M. Springer equal contributor,

    equal contributor Contributed equally to this work with: Nathan M. Springer, Kai Ying

    Affiliation: Department of Plant Biology, University of Minnesota, Saint Paul, Minnesota, United States of America

    X
  • Kai Ying equal contributor,

    equal contributor Contributed equally to this work with: Nathan M. Springer, Kai Ying

    Affiliations: Interdepartmental Genetics Graduate Program, Iowa State University, Ames, Iowa, United States of America, Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa, United States of America

    X
  • Yan Fu,

    Affiliations: Department of Agronomy, Iowa State University, Ames, Iowa, United States of America, Center for Carbon Capturing Crops, Iowa State University, Ames, Iowa, United States of America

    X
  • Tieming Ji,

    Affiliation: Department of Statistics, Iowa State University, Ames, Iowa, United States of America

    X
  • Cheng-Ting Yeh,

    Affiliations: Department of Agronomy, Iowa State University, Ames, Iowa, United States of America, Center for Plant Genomics, Iowa State University, Ames, Iowa, United States of America

    X
  • Yi Jia,

    Affiliation: Interdepartment Plant Biology, Iowa State University, Ames, Iowa, United States of America

    X
  • Wei Wu,

    Affiliations: Department of Agronomy, Iowa State University, Ames, Iowa, United States of America, Center for Plant Genomics, Iowa State University, Ames, Iowa, United States of America

    X
  • Todd Richmond,

    Affiliation: Roche NimbleGen, Madison, Wisconsin, United States of America

    X
  • Jacob Kitzman,

    Affiliation: Roche NimbleGen, Madison, Wisconsin, United States of America

    X
  • Heidi Rosenbaum,

    Affiliation: Roche NimbleGen, Madison, Wisconsin, United States of America

    X
  • A. Leonardo Iniguez,

    Affiliation: Roche NimbleGen, Madison, Wisconsin, United States of America

    X
  • W. Brad Barbazuk,

    Affiliation: University of Florida, Gainesville, Florida, United States of America

    X
  • Jeffrey A. Jeddeloh,

    Affiliation: Roche NimbleGen, Madison, Wisconsin, United States of America

    X
  • Dan Nettleton,

    Affiliation: Department of Statistics, Iowa State University, Ames, Iowa, United States of America

    X
  • Patrick S. Schnable mail

    schnable@iastate.edu

    Affiliations: Interdepartmental Genetics Graduate Program, Iowa State University, Ames, Iowa, United States of America, Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa, United States of America, Department of Agronomy, Iowa State University, Ames, Iowa, United States of America, Center for Carbon Capturing Crops, Iowa State University, Ames, Iowa, United States of America, Center for Plant Genomics, Iowa State University, Ames, Iowa, United States of America, Interdepartment Plant Biology, Iowa State University, Ames, Iowa, United States of America

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  • Published: November 20, 2009
  • DOI: 10.1371/journal.pgen.1000734
  • Featured in PLOS Collections

About the Authors

Nathan M. Springer
Department of Plant Biology, University of Minnesota, Saint Paul, Minnesota, United States of America
Kai Ying, Patrick S. Schnable
Interdepartmental Genetics Graduate Program, Iowa State University, Ames, Iowa, United States of America
Kai Ying, Patrick S. Schnable
Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa, United States of America
Yan Fu, Cheng-Ting Yeh, Wei Wu, Patrick S. Schnable
Department of Agronomy, Iowa State University, Ames, Iowa, United States of America
Yan Fu, Patrick S. Schnable
Center for Carbon Capturing Crops, Iowa State University, Ames, Iowa, United States of America
Tieming Ji, Dan Nettleton
Department of Statistics, Iowa State University, Ames, Iowa, United States of America
Cheng-Ting Yeh, Wei Wu, Patrick S. Schnable
Center for Plant Genomics, Iowa State University, Ames, Iowa, United States of America
Yi Jia, Patrick S. Schnable
Interdepartment Plant Biology, Iowa State University, Ames, Iowa, United States of America
Todd Richmond, Jacob Kitzman, Heidi Rosenbaum, A. Leonardo Iniguez, Jeffrey A. Jeddeloh
Roche NimbleGen, Madison, Wisconsin, United States of America
W. Brad Barbazuk
University of Florida, Gainesville, Florida, United States of America

Corresponding Author

Email: schnable@iastate.edu

Competing Interests

Todd Richmond, Jacob Kitzman, Heidi Rosenbaum, A. Leonardo Iniguez, and Jeffrey A. Jeddeloh are employees of Roche NimbleGen.

Author Contributions

Conceived and designed the experiments: NMS JAJ PSS. Performed the experiments: KY YF YJ WW HR ALI. Analyzed the data: NMS KY YF TJ CTY YJ WW WBB JAJ DN PSS. Contributed reagents/materials/analysis tools: TR JK WBB JAJ. Wrote the paper: NMS PSS.