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Research Article

Acquisition of Aneuploidy Provides Increased Fitness during the Evolution of Antifungal Drug Resistance

  • Anna M. Selmecki,

    Affiliation: Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America

    Current address: Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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  • Keely Dulmage,

    Affiliation: Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Leah E. Cowen,

    Affiliation: Department of Molecular Genetics, University of Toronto, Toronto, Canada

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  • James B. Anderson,

    Affiliation: Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario, Canada

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  • Judith Berman mail

    jberman@umn.edu

    Affiliations: Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Published: October 30, 2009
  • DOI: 10.1371/journal.pgen.1000705

About the Authors

Anna M. Selmecki, Keely Dulmage, Judith Berman
Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America
Leah E. Cowen
Department of Molecular Genetics, University of Toronto, Toronto, Canada
James B. Anderson
Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario, Canada
Judith Berman
Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America

Corresponding Author

Email: jberman@umn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AMS JB. Performed the experiments: AMS KD LEC. Analyzed the data: AMS KD LEC JB. Contributed reagents/materials/analysis tools: AMS JBA JB. Wrote the paper: AMS JB.