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Research Article

Epigenetic and Conventional Regulation Is Distributed among Activators of FLO11 Allowing Tuning of Population-Level Heterogeneity in Its Expression

  • Leah M. Octavio,

    Affiliation: Computational and Systems Biology Initiative, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Kamil Gedeon,

    Affiliation: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Narendra Maheshri mail

    narendra@mit.edu

    Affiliation: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Published: October 02, 2009
  • DOI: 10.1371/journal.pgen.1000673

About the Authors

Leah M. Octavio
Computational and Systems Biology Initiative, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Kamil Gedeon, Narendra Maheshri
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Corresponding Author

Email: narendra@mit.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LO NM. Performed the experiments: LO KG NM. Analyzed the data: LO NM. Contributed reagents/materials/analysis tools: LO NM. Wrote the paper: LO NM.