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Research Article

Compensatory Evolution of Gene Regulation in Response to Stress by Escherichia coli Lacking RpoS

  • Daniel M. Stoebel,

    Affiliation: Department of Microbiology and Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College, Dublin, Ireland

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  • Karsten Hokamp,

    Affiliation: Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College, Dublin, Ireland

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  • Michael S. Last,

    Affiliation: UC Toxic Substance Research and Teaching Program, University of California Davis, Davis, California, United States of America

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  • Charles J. Dorman mail

    cjdorman@tcd.ie

    Affiliation: Department of Microbiology and Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College, Dublin, Ireland

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  • Published: October 02, 2009
  • DOI: 10.1371/journal.pgen.1000671

About the Authors

Daniel M. Stoebel, Charles J. Dorman
Department of Microbiology and Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College, Dublin, Ireland
Karsten Hokamp
Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College, Dublin, Ireland
Michael S. Last
UC Toxic Substance Research and Teaching Program, University of California Davis, Davis, California, United States of America

Corresponding Author

Email: cjdorman@tcd.ie

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DMS CJD. Performed the experiments: DMS. Analyzed the data: DMS KH MSL CJD. Wrote the paper: DMS CJD.