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Research Article

Run-Off Replication of Host-Adaptability Genes Is Associated with Gene Transfer Agents in the Genome of Mouse-Infecting Bartonella grahamii

  • Eva C. Berglund,

    Affiliation: Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden

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  • A. Carolin Frank,

    Affiliation: Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden

    Current address: School of Natural Sciences, University of California, Merced, California, United States of America

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  • Alexandra Calteau,

    Affiliation: Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden

    Current address: CNRS UMR8030, Génomique Métabolique, and CEA - Institut de Génomique - Genoscope, Laboratoire de Génomique Comparative, Evry, France

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  • Olga Vinnere Pettersson,

    Affiliation: Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden

    Current address: Department of Microbiology, The Swedish Agricultural University, Uppsala, Sweden

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  • Fredrik Granberg,

    Affiliation: Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden

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  • Ann-Sofie Eriksson,

    Affiliation: Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden

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  • Kristina Näslund,

    Affiliation: Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden

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  • Martin Holmberg,

    Affiliation: Department of Medical Sciences, Section for Infectious Diseases, Uppsala University Hospital, Uppsala, Sweden

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  • Hillevi Lindroos †,

    † Deceased.

    Affiliation: Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden

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  • Siv G. E. Andersson mail

    Siv.Andersson@ebc.uu.se

    Affiliation: Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden

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  • Published: July 03, 2009
  • DOI: 10.1371/journal.pgen.1000546

About the Authors

Eva C. Berglund, A. Carolin Frank, Alexandra Calteau, Olga Vinnere Pettersson, Fredrik Granberg, Ann-Sofie Eriksson, Kristina Näslund, Hillevi Lindroos, Siv G. E. Andersson
Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
Martin Holmberg
Department of Medical Sciences, Section for Infectious Diseases, Uppsala University Hospital, Uppsala, Sweden

Corresponding Author

Email: Siv.Andersson@ebc.uu.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SGEA. Performed the experiments: ECB OVP FG ASE KN. Analyzed the data: ECB ACF AC SGEA. Contributed reagents/materials/analysis tools: MH HL. Wrote the paper: ECB ACF SGEA.