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Research Article

Genome-Wide Identification of Alternative Splice Forms Down-Regulated by Nonsense-Mediated mRNA Decay in Drosophila

  • Kasper Daniel Hansen equal contributor,

    equal contributor Contributed equally to this work with: Kasper Daniel Hansen, Liana F. Lareau

    Affiliation: Division of Biostatistics, School of Public Health, University of California Berkeley, Berkeley, California, United States of America

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  • Liana F. Lareau equal contributor,

    equal contributor Contributed equally to this work with: Kasper Daniel Hansen, Liana F. Lareau

    Affiliations: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America, Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, California, United States of America

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  • Marco Blanchette,

    Affiliations: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America, Stowers Institute for Medical Research, Kansas City, Missouri, United States of America

    X
  • Richard E. Green,

    Affiliations: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America, Max-Planck Institute for Evolutionary Anthropology, Leipzig, Germany

    X
  • Qi Meng,

    Affiliation: Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, California, United States of America

    X
  • Jan Rehwinkel,

    Affiliation: Max-Planck Institute for Developmental Biology, Tuebingen, Germany

    Current address: Cancer Research UK London Research Institute, London, United Kingdom

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  • Fabian L. Gallusser,

    Affiliation: Division of Biostatistics, School of Public Health, University of California Berkeley, Berkeley, California, United States of America

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  • Elisa Izaurralde,

    Affiliation: Max-Planck Institute for Developmental Biology, Tuebingen, Germany

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  • Donald C. Rio,

    Affiliation: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America

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  • Sandrine Dudoit,

    Affiliation: Division of Biostatistics, School of Public Health, University of California Berkeley, Berkeley, California, United States of America

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  • Steven E. Brenner mail

    brenner@compbio.berkeley.edu

    Affiliations: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America, Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, California, United States of America

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  • Published: June 19, 2009
  • DOI: 10.1371/journal.pgen.1000525

About the Authors

Kasper Daniel Hansen, Fabian L. Gallusser, Sandrine Dudoit
Division of Biostatistics, School of Public Health, University of California Berkeley, Berkeley, California, United States of America
Liana F. Lareau, Marco Blanchette, Richard E. Green, Donald C. Rio, Steven E. Brenner
Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America
Liana F. Lareau, Qi Meng, Steven E. Brenner
Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, California, United States of America
Marco Blanchette
Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
Richard E. Green
Max-Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Jan Rehwinkel, Elisa Izaurralde
Max-Planck Institute for Developmental Biology, Tuebingen, Germany

Corresponding Author

Email: brenner@compbio.berkeley.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KDH LFL MB REG QM DCR SD SEB. Performed the experiments: MB QM. Analyzed the data: KDH LFL MB REG QM FLG DCR SD SEB. Contributed reagents/materials/analysis tools: JR EI. Wrote the paper: KDH LFL SD SEB.