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Research Article

Discovery of Rare Variants via Sequencing: Implications for the Design of Complex Trait Association Studies

  • Bingshan Li,

    Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Suzanne M. Leal mail

    sleal@bcm.edu

    Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Published: May 15, 2009
  • DOI: 10.1371/journal.pgen.1000481

About the Authors

Bingshan Li, Suzanne M. Leal
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Corresponding Author

Email: sleal@bcm.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SML. Performed the experiments: BL. Analyzed the data: BL. Wrote the paper: BL SML.