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Research Article

Genetic Evidence That the Non-Homologous End-Joining Repair Pathway Is Involved in LINE Retrotransposition

  • Jun Suzuki equal contributor,

    equal contributor Contributed equally to this work with: Jun Suzuki, Katsumi Yamaguchi

    Affiliation: Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Midori-ku, Yokohama, Kanagawa, Japan

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  • Katsumi Yamaguchi equal contributor,

    equal contributor Contributed equally to this work with: Jun Suzuki, Katsumi Yamaguchi

    Affiliation: Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Midori-ku, Yokohama, Kanagawa, Japan

    X
  • Masaki Kajikawa mail,

    mkaji@bio.titech.ac.jp (MK); nokada@bio.titech.ac.jp (NO)

    Affiliation: Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Midori-ku, Yokohama, Kanagawa, Japan

    X
  • Kenji Ichiyanagi,

    Affiliation: Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Research Organization of Information and Systems, Mishima, Shizuoka, Japan

    X
  • Noritaka Adachi,

    Affiliation: International Graduate School of Arts and Sciences, Yokohama City University, Kanazawa-ku, Yokohama, Kanagawa, Japan

    X
  • Hideki Koyama,

    Affiliation: International Graduate School of Arts and Sciences, Yokohama City University, Kanazawa-ku, Yokohama, Kanagawa, Japan

    X
  • Shunichi Takeda,

    Affiliation: Radiation Genetics, Graduate School of Medicine, Kyoto University, Konoe Yoshida, Kyoto, Kyoto, Japan

    X
  • Norihiro Okada mail

    mkaji@bio.titech.ac.jp (MK); nokada@bio.titech.ac.jp (NO)

    Affiliation: Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Midori-ku, Yokohama, Kanagawa, Japan

    X
  • Published: April 24, 2009
  • DOI: 10.1371/journal.pgen.1000461

About the Authors

Jun Suzuki, Katsumi Yamaguchi, Masaki Kajikawa, Norihiro Okada
Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Midori-ku, Yokohama, Kanagawa, Japan
Kenji Ichiyanagi
Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Research Organization of Information and Systems, Mishima, Shizuoka, Japan
Noritaka Adachi, Hideki Koyama
International Graduate School of Arts and Sciences, Yokohama City University, Kanazawa-ku, Yokohama, Kanagawa, Japan
Shunichi Takeda
Radiation Genetics, Graduate School of Medicine, Kyoto University, Konoe Yoshida, Kyoto, Kyoto, Japan

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JS MK NO. Performed the experiments: JS KY MK. Analyzed the data: JS KY MK. Contributed reagents/materials/analysis tools: NA HK ST. Wrote the paper: MK KI NO.