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Research Article

Capturing the Spectrum of Interaction Effects in Genetic Association Studies by Simulated Evaporative Cooling Network Analysis

  • Brett A. McKinney mail,

    brett.mckinney@gmail.com

    Affiliation: Department of Genetics, University of Alabama School of Medicine, Birmingham, Alabama, United States of America

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  • James E. Crowe Jr,

    Affiliation: Departments of Pediatrics, Microbiology and Immunology, Program in Vaccine Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Jingyu Guo,

    Affiliation: Department of Genetics, University of Alabama School of Medicine, Birmingham, Alabama, United States of America

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  • Dehua Tian

    Affiliation: Department of Genetics, University of Alabama School of Medicine, Birmingham, Alabama, United States of America

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  • Published: March 20, 2009
  • DOI: 10.1371/journal.pgen.1000432

About the Authors

Brett A. McKinney, Jingyu Guo, Dehua Tian
Department of Genetics, University of Alabama School of Medicine, Birmingham, Alabama, United States of America
James E. Crowe Jr
Departments of Pediatrics, Microbiology and Immunology, Program in Vaccine Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Corresponding Author

Email: brett.mckinney@gmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BAM. Performed the experiments: BAM JG DT. Analyzed the data: BAM. Contributed reagents/materials/analysis tools: JEC. Wrote the paper: BAM.