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Research Article

Ploidy Reductions in Murine Fusion-Derived Hepatocytes

  • Andrew W. Duncan mail,

    duncanan@ohsu.edu

    Affiliation: Oregon Stem Cell Center, Oregon Health and Science University, Portland, Oregon, United States of America

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  • Raymond D. Hickey,

    Affiliations: Oregon Stem Cell Center, Oregon Health and Science University, Portland, Oregon, United States of America, Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America

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  • Nicole K. Paulk,

    Affiliation: Oregon Stem Cell Center, Oregon Health and Science University, Portland, Oregon, United States of America

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  • Andrew J. Culberson,

    Affiliation: Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America

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  • Susan B. Olson,

    Affiliation: Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America

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  • Milton J. Finegold,

    Affiliation: Department of Pathology, Texas Children's Hospital, Houston, Texas, United States of America

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  • Markus Grompe

    Affiliations: Oregon Stem Cell Center, Oregon Health and Science University, Portland, Oregon, United States of America, Papé Family Research Institute, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon, United States of America

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  • Published: February 20, 2009
  • DOI: 10.1371/journal.pgen.1000385

About the Authors

Andrew W. Duncan, Raymond D. Hickey, Nicole K. Paulk, Markus Grompe
Oregon Stem Cell Center, Oregon Health and Science University, Portland, Oregon, United States of America
Raymond D. Hickey, Andrew J. Culberson, Susan B. Olson
Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America
Milton J. Finegold
Department of Pathology, Texas Children's Hospital, Houston, Texas, United States of America
Markus Grompe
Papé Family Research Institute, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon, United States of America

Corresponding Author

Email: duncanan@ohsu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AWD MG. Performed the experiments: AWD RDH. Analyzed the data: AWD RDH AJC SBO MJF MG. Contributed reagents/materials/analysis tools: AWD NKP. Wrote the paper: AWD.