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Research Article

Identification of a Shared Genetic Susceptibility Locus for Coronary Heart Disease and Periodontitis

  • Arne S. Schaefer mail,

    a.schaefer@ikmb.uni-kiel.de

    Affiliation: Institute for Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Gesa M. Richter,

    Affiliation: Institute for Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Birte Groessner-Schreiber,

    Affiliation: Department of Operative Dentistry and Periodontology, University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Barbara Noack,

    Affiliation: University Medical Center Carl Gustav Carus der Technischen Universität Dresden, Zentrum für Zahn-, Mund- und Kieferheilkunde, Poliklinik für Zahnerhaltung, Dresden, Germany

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  • Michael Nothnagel,

    Affiliation: Institute of Medical Informatics and Statistics, University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Nour-Eddine El Mokhtari,

    Affiliation: Clinic of Cardiology, University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Bruno G. Loos,

    Affiliation: Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), VU University Amsterdam, Amsterdam, The Netherlands

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  • Søren Jepsen,

    Affiliation: Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany

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  • Stefan Schreiber

    Affiliation: Institute for Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Published: February 13, 2009
  • DOI: 10.1371/journal.pgen.1000378

About the Authors

Arne S. Schaefer, Gesa M. Richter, Stefan Schreiber
Institute for Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Kiel, Germany
Birte Groessner-Schreiber
Department of Operative Dentistry and Periodontology, University Medical Center Schleswig-Holstein, Kiel, Germany
Barbara Noack
University Medical Center Carl Gustav Carus der Technischen Universität Dresden, Zentrum für Zahn-, Mund- und Kieferheilkunde, Poliklinik für Zahnerhaltung, Dresden, Germany
Michael Nothnagel
Institute of Medical Informatics and Statistics, University Medical Center Schleswig-Holstein, Kiel, Germany
Nour-Eddine El Mokhtari
Clinic of Cardiology, University Medical Center Schleswig-Holstein, Kiel, Germany
Bruno G. Loos
Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), VU University Amsterdam, Amsterdam, The Netherlands
Søren Jepsen
Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany

Corresponding Author

Email: a.schaefer@ikmb.uni-kiel.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ASS. Performed the experiments: ASS GMR. Analyzed the data: ASS GMR MN. Contributed reagents/materials/analysis tools: BGS BN NEEM BGL SJ SS. Wrote the paper: ASS.