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Research Article

Accumulation of Rhodopsin in Late Endosomes Triggers Photoreceptor Cell Degeneration

  • Yashodhan Chinchore,

    Affiliation: Department of Biology, Dartmouth College, Hanover, New Hampshire, United States of America

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  • Amitavo Mitra,

    Affiliation: Department of Biology, Dartmouth College, Hanover, New Hampshire, United States of America

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  • Patrick J. Dolph mail

    patrick.dolph@dartmouth.edu

    Affiliation: Department of Biology, Dartmouth College, Hanover, New Hampshire, United States of America

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  • Published: February 13, 2009
  • DOI: 10.1371/journal.pgen.1000377

About the Authors

Yashodhan Chinchore, Amitavo Mitra, Patrick J. Dolph
Department of Biology, Dartmouth College, Hanover, New Hampshire, United States of America

Corresponding Author

Email: patrick.dolph@dartmouth.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YC PJD. Performed the experiments: YC AM. Analyzed the data: YC PJD. Contributed reagents/materials/analysis tools: YC PJD. Wrote the paper: YC.